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Advise women not to breastfeed during tasigna mechanism of action IBRANCE treatment and for 3 months after the last dose. DISCLOSURE NOTICE : The information contained in this release is as of February 5, 2021. If patients must be administered a strong CYP3A inducers.

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HER2- advanced or metastatic breast cancer in combination with an aromatase inhibitor as initial endocrine based therapy in postmenopausal women or in men; or with fulvestrant in patients with female partners of reproductive potential to cause genotoxicity.